Thermo Fisher Scientific RKHD2 Polyclonal Antibody
RKHD2 단백질을 인식하는 Thermo Fisher Scientific의 염소 다클론 항체로, Western blot과 IHC(P)에서 검증됨. Human 및 Mouse 반응성. 비표지형 액상 항체로, TBS(pH 7.3) 및 0.5% BSA 보존. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–0.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-TPRLSPTFPESIEH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933548 |
Product Specific Information
This antibody is tested in Peptide ELISA with an antibody detection limit dilution of 1:32,000.
Target Information
Rkhd2, also known as MEX3C, belongs to a novel family of four homologous human MEX3 proteins, each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module.
MEX3 proteins, including Rkhd2, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and cytoplasm via the CRM1 export pathway.
These proteins are evolutionarily conserved RNA-binding proteins involved in post-transcriptional regulatory mechanisms.
Genetic variations in Rkhd2 may be associated with susceptibility to essential hypertension type 8.
Rkhd3 and Rkhd4, but not Rkhd2, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), which are centers of mRNA turnover.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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