Thermo Fisher Scientific RGS21 Polyclonal Antibody
RGS21 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합. Human, Mouse, Rat 반응성. 고순도 Protein A 정제, 안정적 액상 형태로 -20°C 보관.
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Thermo Fisher Scientific RGS21 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human RGS21, amino acids 21–120 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Regulator of G-protein signaling (RGS) proteins contain a conserved 120 amino acid domain termed the RGS domain, which acts as a GTPase-activating protein to reduce signaling from receptor-activated G-alpha subunits.
RGS21 is a newly identified member of this family, selectively expressed in subpopulations of taste bud cells and co-expressed with bitter and sweet transduction components such as alpha-gusticin, phospholipase Cβ2, T1R2/T1R3 sweet taste receptors, and T2R bitter taste receptors.
Binding assays show that RGS21 interacts with alpha-gusticin and possibly T1R receptors, suggesting a role in sweet and bitter taste transduction processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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