Thermo Fisher Scientific Oxytocin Receptor Recombinant Rabbit Monoclonal Antibody (7X8B8)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

7X8B8

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Oxytocin Receptor (P30559) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Oxytocin Receptor,uniProtId:P30559-1,ncbiNodeId:9606,antigenRange:50-150,antigenLength:389,antigenImageFileName:MA5-37974_Oxytocin_Receptor_P30559-1_Rabbit.svg,antigenImageFileNamePDP:MA5-37974_Oxytocin_Receptor_P30559-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.2 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2897892

Product Specific Information

Positive Samples: HeLa, PC-3, Jukat, Mouse brain

Immunogen sequence: LLLALSGNAC VLLALRTTRQ KHSRLFFFMK HLSIADLVVA VFQVLPQLLW DITFRFYGPD LLCRLVKYLQ VVGMFASTYL LLLMSLDRCL AICQPLRSLR R

Target Information

The oxytocin receptor (OXTR) belongs to the G-protein coupled receptor family. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The receptor is made up of 389 amino acids and has a molecular weight of ~43,000 kDa. The oxytocin-oxytocin receptor system plays an important role as an inducer of uterine contractions during parturition and of milk ejection. Oxytocin receptors are expressed by the myoepithelial cells of the mammary gland, and in both the myometrium and endometrium or the uterus at the end of pregnancy. Additionally, oxytocin receptors are present in the central nervous system, mediating a variety of behaviors, including maternal behavior, bonding, social memory and recognition, sexual and aggressive behaviors, and stress and anxiety.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.