Thermo Fisher Scientific DUSP3 Polyclonal Antibody
Human DUSP3 단백질을 인식하는 Rabbit Polyclonal 항체로, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼와 글리세롤로 안정화되어 있습니다. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5111569
- 판매단위
- pk
카탈로그
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DUSP3 (Product # RP-107263) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2856979 |
Product Specific Information
Immunogen sequence:
LVIAYLMMRQ KMDVKSALSI VRQNREIGPN DGFLAQLCQL NDRLAKEGKL KP
Target Information
Protein tyrosine phosphatases (PTPs) are enzymes that remove phosphate groups from phosphorylated tyrosine residues on proteins. Together with tyrosine kinases, they regulate the phosphorylation state of key signaling molecules, including the MAP kinase family.
Dual specificity phosphatases (DSPs) are a subclass of the PTP superfamily that dephosphorylate both phosphothreonine and phosphotyrosine residues. The VH1 gene in vaccinia virus is a prototypical DSP expressed during late-stage infection. The shallow active site of VHR allows hydrolysis of phosphorylated serine, threonine, or tyrosine residues, unlike the deeper active site of typical PTPs which restricts specificity to phosphotyrosine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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