Thermo Fisher Scientific Claudin 6 Polyclonal Antibody
Claudin 6 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인체 시료 반응성. PBS/glycerol buffer에 보관되며, 연구용으로 적합. 긴밀결합(tight junction) 연구에 유용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region 85–116 aa of Claudin 6 (UniProt ID: P56747-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Selective precipitation |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2718253 |
Target Information
Tight junctions are a form of cell-to-cell adhesion in epithelial or endothelial sheets, forming continuous seals around cells and serving as a barrier to prevent solutes and water from passing freely through the paracellular space. These junctions consist of continuous networking strands in the cytoplasmic leaflet with complementary grooves in the extracytoplasmic leaflet.
The Claudin 6 gene encodes a component of tight junction strands, belonging to the claudin family. This integral membrane protein functions as one of the entry cofactors for hepatitis C virus. Gene methylation may be involved in esophageal tumorigenesis. The gene is located adjacent to CLDN9 on chromosome 16.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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