Thermo Fisher Scientific CRSP130 Polyclonal Antibody
Human MED23를 인식하는 Rabbit Polyclonal Antibody로, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공합니다. PBS 기반 용액 형태로 4°C 또는 -20°C에서 안정적으로 보관 가능합니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MED23. Recombinant protein control fragment (Product #RP-105501) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2791988 |
Product Specific Information
Immunogen Sequence:
PATLRFPLKG LLPYDKDLFE PQTALLRYVL EQPYSRDMVC NMLGLNKQHK QRCPVLEDQL VDLVVYAMER SETEEKFDDG
Target Information
CRSP is ubiquitously expressed in various tissues and functions as a multimeric complex consisting of nine distinct subunits. Several members of the CRSP family share sequence similarity with multiple components of yeast transcriptional mediator proteins, including CRSP150 (related to yeast Rgr1) and CRSP70 (similar to elongation factor TFIIS). CRSP77 and CRSP150 are related to proteins within the murine mediator complex, while CRSP130 and CRSP34 are largely unrelated to murine or yeast proteins.
CRSP subunits also associate with larger multimeric co-activator complexes, including ARC/DRI (binds directly to SREBP and nuclear hormone receptors to facilitate transcription) and NAT (a polymerase II-interacting complex that represses activated transcription).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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