Thermo Fisher Scientific Calreticulin Recombinant Mouse Monoclonal Antibody (2E2)
Calreticulin 단백질을 인식하는 Mouse Recombinant Monoclonal Antibody (Clone 2E2). Western blot, IHC, ICC, Flow cytometry, ELISA 등 다양한 응용 가능. Human 및 Mouse 반응성. 고순도 Affinity chromatography 정제, 안정적 액상 형태로 제공.
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Thermo Fisher Scientific Calreticulin Recombinant Mouse Monoclonal Antibody (2E2)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:200 |
| Immunocytochemistry (ICC/IF) | 1:20–1:200 |
| Flow Cytometry (Flow) | 1:20–1:200 |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 2E2 |
| Immunogen | Recombinant Human CALR protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.833 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3093684 |
Target Information
Calreticulin (Calr) is a calcium-binding chaperone that promotes folding, oligomeric assembly, and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. Calr, a lectin, interacts transiently with most monoglucosylated glycoproteins synthesized in the ER. It also interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Additionally, Calr may be involved in maternal gene expression regulation and oocyte maturation through calcium homeostasis regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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