Thermo Fisher Scientific F2 Monoclonal Antibody (1B19)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

ELISA (ELISA)

0.03 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

1B19

Immunogen

F2 (AAH51332, 263 a.a. approximately 362 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Prothrombin,uniProtId:P00734-1,ncbiNodeId:9606,antigenRange:263-362,antigenLength:622,antigenImageFileName:H00002147-M02_Prothrombin_P00734-1_House_mouse.svg,antigenImageFileNamePDP:H00002147-M02_Prothrombin_P00734-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: RNPDGDEEGA WCYVAGKPGD FGYCDLNYCE EAVEEETGDG LDEDSDRAIE GRTATSEYQT FFNPRTFGSG EADCGLRPLF EKKSLEDKTE RELLESYIDG

Target Information

Prothrombin or Coagulation factor II, is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.