Thermo Fisher Scientific KERA Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

1:50-1:200

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human KERA

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642985

Product Specific Information

Immunogen sequence: SRSVRQVYEV HDSDDWTIHD FECPMECFCP PSFPTALYCE NRGLKEIPAI PSRIWYLYL

Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 77%.

Target Information

Keratocan (KTN), also known as keratan sulfate proteoglycan keratocan, is a protein that in humans is encoded by the KERA gene. It is mapped to 12q22. The protein encoded by this gene is a keratan sulfate proteoglycan that is involved in corneal transparency. Defects in this gene are a cause of autosomal recessive cornea plana 2 (CNA2). Keratan sulfate proteoglycans (KSPGs) are members of the small leucine-rich proteoglycan (SLRP) family. KSPGs, particularly keratocan, lumican and mimecan, are important to the transparency of the cornea.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.