Thermo Fisher Scientific Apolipoprotein L3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-331 of human APOL3 (NP_6636141) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Apolipoprotein L3,uniProtId:O95236-1,ncbiNodeId:9606,antigenRange:1-331,antigenLength:402,antigenImageFileName:PA5-89476_Apolipoprotein_L3_O95236-1_Rabbit.svg,antigenImageFileNamePDP:PA5-89476_Apolipoprotein_L3_O95236-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.75 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805594

Product Specific Information

Immunogen sequence: MDSEKKRFTE EATKYFRERV SPVHLQILLT NNEAWKRFVT AAELPRDEAD ALYEALKKLR TYAAIEDEYV QQKDEQFREW FLKEFPQVKR KIQESIEKLR ALANGIEEVH RGCTISNVVS SSTGAASGIM SLAGLVLAPF TAGTSLALTA AGVGLGAASA VTGITTSIVE HSYTSSAEAE ASRLTATSID RLKVFKEVMR DITPNLLSLL NNYYEATQTI GSEIRAIRQA RARARLPVTT WRISAGSGGQ AERTIAGTTR AVSRGARILS ATTSGIFLAL DVVNLVYESK HLHEGAKSAS AEELRRQAQE LEENLMELTQ IYQRLNPCHT H; Positive Samples: DU145, A-549, BxPC-3, Mouse kidney; Cellular Location: Cytoplasm

Target Information

Apolipoproteins are protein components of plasma lipoproteins. The apolipoprotein L gene family encodes six highly homologous proteins designated apoL1-6, which are associated with large high density type lipoproteins (HDL). The human apoL family maps to chromosome 22q12.1-13.1 within a 127,000 bp region. apoL2 and apoL3 may allow the binding of lipids to organelles or may be involved in the movement of lipids in the cytoplasm. apoL2 localizes to the cytoplasm and is widely expressed, with the highest levels observed in the lung, thymus, pancreas, placenta, adult brain and prostate. The apoL2 protein is also detected in the spleen, liver, kidney, colon, small intestine, uterus, spinal cord, adrenal gland, salivary gland, trachea, mammary gland, skeletal muscle, testis and fetal brain and liver. apoL3 also localizes to the cytoplasm and is widely expressed, with highest levels detected in the prostate, lung and placenta. It is also detected in kidney, bone marrow, spleen, thymus, spinal cord, adrenal gland, salivary gland, trachea and mammary gland. Lower levels of apoL3 are observed in the brain, heart, fetal liver, pancreas and testis.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.