Thermo Fisher Scientific Apolipoprotein L3 Polyclonal Antibody
Thermo Fisher Scientific의 Apolipoprotein L3 폴리클로날 항체는 Human과 Mouse 시료에 반응하며, Western blot과 ELISA에 적합합니다. Rabbit IgG 기반의 액상 항체로, PBS와 글리세롤 버퍼에 보관되며 -20°C에서 안정적으로 유지됩니다. 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–331 of human APOL3 (NP_663614.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.75 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805594 |
Product Specific Information
Immunogen sequence:
MDSEKKRFTE EATKYFRERV SPVHLQILLT NNEAWKRFVT AAELPRDEAD ALYEALKKLR TYAAIEDEYV QQKDEQFREW FLKEFPQVKR KIQESIEKLR ALANGIEEVH RGCTISNVVS SSTGAASGIM SLAGLVLAPF TAGTSLALTA AGVGLGAASA VTGITTSIVE HSYTSSAEAE ASRLTATSID RLKVFKEVMR DITPNLLSLL NNYYEATQTI GSEIRAIRQA RARARLPVTT WRISAGSGGQ AERTIAGTTR AVSRGARILS ATTSGIFLAL DVVNLVYESK HLHEGAKSAS AEELRRQAQE LEENLMELTQ IYQRLNPCHT H
Positive Samples: DU145, A-549, BxPC-3, Mouse kidney
Cellular Location: Cytoplasm
Target Information
Apolipoproteins are protein components of plasma lipoproteins. The apolipoprotein L gene family encodes six highly homologous proteins designated apoL1–6, which are associated with large high-density type lipoproteins (HDL). The human apoL family maps to chromosome 22q12.1–13.1 within a 127,000 bp region.
apoL2 and apoL3 may allow the binding of lipids to organelles or may be involved in the movement of lipids in the cytoplasm. apoL2 localizes to the cytoplasm and is widely expressed, with the highest levels observed in the lung, thymus, pancreas, placenta, adult brain, and prostate. The apoL2 protein is also detected in spleen, liver, kidney, colon, small intestine, uterus, spinal cord, adrenal gland, salivary gland, trachea, mammary gland, skeletal muscle, testis, and fetal brain and liver.
apoL3 also localizes to the cytoplasm and is widely expressed, with highest levels detected in the prostate, lung, and placenta. It is also detected in kidney, bone marrow, spleen, thymus, spinal cord, adrenal gland, salivary gland, trachea, and mammary gland. Lower levels of apoL3 are observed in the brain, heart, fetal liver, pancreas, and testis.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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