Thermo Fisher Scientific HS2ST1 Polyclonal Antibody
HS2ST1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 ELISA에 적합하며, 인간, 마우스, 랫트 시료에서 반응. 액상 형태로 공급되며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–229 of human HS2ST1 (NP_001127964.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.69 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805591 |
Product Specific Information
Immunogen sequence:
MGLLRIMMPP KLQLLAVVAF AVAMLFLENQ IQKLEESRSK LERAIARHEV REIEQRHTMD GPRQDATLDE EEDMVIIYNR VPKTASTSFT NIAYDLCAKN KYHVLHINTT KNNPVMSLQD QVRFVKNITS WKEMKPGFYH GHVSYLDFAK FGVKKKPIYI NVIRDPIERL VSYYYFLRFG DDYRPGLRRR KQGDKKTFDE CVAEGGSDCA PEKLWLQIPF FCGHSSECW
Positive Samples: U-87MG, Mouse lung, Rat thymus
Cellular Location: Golgi apparatus membrane, Single-pass type II membrane protein
Target Information
Heparan sulfate biosynthetic enzymes are key components in generating distinct heparan sulfate fine structures that mediate multiple biological activities.
The HS2ST1 gene encodes an enzyme that transfers sulfate to the 2-position of the iduronic acid residue of heparan sulfate.
Disruption of this gene in knockout mice results in the absence of kidney formation, indicating its essential role in signaling during kidney development.
Two alternatively spliced transcript variants encoding different proteins have been identified.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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