Thermo Fisher Scientific MEP1B Polyclonal Antibody
Rabbit polyclonal antibody against human MEP1B, validated for IHC (Paraffin). Recognizes recombinant human MEP1B protein. Supplied as liquid, unconjugated, 0.05 mg/mL in PBS with 40% glycerol. For research use only.
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Applications and Tested Dilution
- Application: Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MEP1B. Recombinant protein control fragment (Product #RP-102555) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790220 |
Product Specific Information
Immunogen sequence:
MTTDNGNYFW DRPSKVGTVA LFPNGTQFRR GGGYGTSAFI THERLKSRDF IKGDDVYILL TVEDISHLNS TQIQLTPAPS VQDLCSKTTC KNDGVCTVRD GKAECRC
Target Information
Meprins are multidomain zinc metalloproteases highly expressed in mammalian kidney and intestinal brush border membranes, leukocytes, and certain cancer cells. They hydrolyze various peptide and protein substrates and are implicated in cancer and intestinal inflammation. Mature meprins form oligomers of alpha and/or beta subunits: alpha homooligomers are secreted, while beta-containing oligomers are membrane-bound. The MEP1B gene encodes the beta subunit. Gene disruption in mice affects embryonic viability, renal gene expression, and alpha subunit distribution in kidney and intestine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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