Thermo Fisher Scientific INCA1 Polyclonal Antibody
INCA1 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간 시료에 반응합니다. 세포면역형광(ICC/IF)에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. CDK2 복합체 억제 관련 연구에 활용 가능합니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human INCA1. Recombinant protein control fragment (Product #RP-106394) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2663189 |
Product Specific Information
Immunogen sequence:
LEEERATYPQE EDRFLTPGRA QLLWSPWSPL DQEEACASRQ LHSLASFSTV TARRNPLHNP WGMELAASE
- Highest antigen sequence identity to orthologs: mouse 56%, rat 61%
Target Information
Binds to CDK2-bound cyclins and inhibits the kinase activity of CDK2; binding to cyclins is critical for its function as a CDK inhibitor (PubMed:21540187).
Inhibits cell growth and proliferation, playing a role in cell cycle control.
Required for ING5-mediated regulation of S-phase progression, enhancement of Fas-induced apoptosis, and inhibition of cell growth. [UniProt]
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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