Thermo Fisher Scientific INCA1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human INCA1. Recombinant protein control fragment (Product #RP-106394). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:INCA1,uniProtId:Q0VD86-1,ncbiNodeId:9606,antigenRange:166-235,antigenLength:236,antigenImageFileName:PA5-65720_INCA1_Q0VD86-1_Rabbit.svg,antigenImageFileNamePDP:PA5-65720_INCA1_Q0VD86-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2663189

Product Specific Information

Immunogen sequence: LEEERATYPQE EDRFLTPGRA QLLWSPWSPL DQEEACASRQ LHSLASFSTV TARRNPLHNP WGMELAASE

Highest antigen sequence identity to the following orthologs - mouse 56%, rat 61%.

Target Information

Binds to CDK2-bound cyclins and inhibits the kinase activity of CDK2; binding to cyclins is critical for its function as CDK inhibitor (PubMed:21540187). Inhibits cell growth and cell proliferation and may play a role in cell cycle control. Required for ING5-mediated regulation of S-phase progression, enhancement of Fas-induced apoptosis and inhibition of cell growth. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.