Thermo Fisher Scientific AMZ2 Polyclonal Antibody
Thermo Fisher Scientific AMZ2 폴리클로날 항체는 인간 AMZ2 단백질을 표적으로 하는 토끼 IgG 항체입니다. 면역세포화학(ICC/IF)에 적합하며 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 4°C 또는 -20°C에서 안정적으로 보관 가능합니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human AMZ2 (Recombinant protein control fragment, Product #RP-106395) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663909 |
Product Specific Information
- Immunogen sequence:
PICLHKLQCAV GFSIVERYKA LVRWIDDESS DTPGATPEHS HEDNGNLPKP VEAFKEWKEW II - Highest antigen sequence identity to orthologs: mouse 67%, rat 70%
Target Information
AMZ2 (archaelysin family metallopeptidase 2), also known as archaemetzincin-2 or archeobacterial metalloproteinase-like protein 2, is a 360 amino acid protein belonging to the peptidase M54 family.
Encoded by a gene that maps to human chromosome 17q24.2, AMZ2 is predominantly expressed in heart and testis, and also found in kidney, liver, pancreas, lung, brain, and placenta, as well as fetal tissues such as kidney, liver, lung, and brain.
AMZ2 participates in metal ion binding and functions as a zinc metalloprotease. It is inhibited by general metalloprotease inhibitors o-phenanthroline and batimastat. Exhibiting aminopeptidase activity, AMZ2 acts against Angiotensin in vitro but does not hydrolyze Neurogranin or Angiotensin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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