Thermo Fisher Scientific TACR1 Polyclonal Antibody
TACR1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P/F), ICC/IF 등 다양한 응용에 사용 가능. 인간, 마우스, 랫 등 반응. 보존제 무첨가 전혈청 형태로 제공되며, 신경계 및 염증 관련 연구에 적합.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:100–1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:1,000 | – |
| Immunocytochemistry (ICC/IF) | 1:100 | – |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Dog, Guinea pig, Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Raised against a synthetic peptide at the C-terminus of rat NK-1 conjugated to bovine thyroglobulin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4 °C short term. For long-term storage, store at −20 °C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1958927 |
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Tachykinin Receptor 1 (TACR1), a member of the Tachykinin Receptor subfamily, mediates phosphatidylinositol metabolism via the tachykinin substance P (neurokinin 1). It plays a role in depression, anxiety, and stress regulation, and contributes to behavioral responses, neuronal survival, and cardiovascular and respiratory functions. TACR1 is implicated in the progression of rheumatoid arthritis and osteoarthritis. Two splice variants are known. Expression is mainly in brain, blood lymphocytes, nose, small intestine, and stomach. ESTs have been isolated from brain and spleen libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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