Thermo Fisher Scientific TK1 Polyclonal Antibody
Rabbit polyclonal antibody against human TK1, validated for WB and IP applications. Recognizes residues 205–234 of thymidine kinase 1. Supplied as an unconjugated liquid at 1 mg/mL, stored at 4°C. For research use only.
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 205 and 234 of Human thymidine kinase 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Thymidine Kinase (TK1) is a highly conserved phosphotransferase present in most living cells. It catalyzes the phosphorylation reaction:
deoxythymidine + ATP → deoxythymidine 5'-phosphate + ADP.
TK1 is involved in DNA synthesis and is required for the action of many antiviral drugs, such as azidothymidine (AZT). It is also used in the selection of hybridoma cell lines for monoclonal antibody production and has clinical relevance as it is expressed in proliferating cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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