Thermo Fisher Scientific p66beta/GATAD2B Polyclonal Antibody
Rabbit polyclonal antibody against human p66β/GATAD2B for WB, IHC, and IP applications. Recognizes residues 50–100 of the transcription repressor component in the MeCP1 complex. Supplied as unconjugated liquid, 0.2 mg/mL, stored at 4°C. For research us...
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Thermo Fisher Scientific p66β/GATAD2B Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 50 and 100 of human transcription repressor p66β component of the MeCP1 complex (GATA zinc finger domain containing 2B) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
Target Information
This gene encodes a zinc finger protein transcriptional repressor. The encoded protein is part of the methyl-CpG-binding protein-1 complex, which represses gene expression by deacetylating methylated nucleosomes. Mutations in this gene are linked to intellectual disability and dysmorphic features associated with cognitive disability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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