Thermo Fisher Scientific CCR4-NOT Polyclonal Antibody, Biotin

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1:10,000

-

Immunoprecipitation (IP)

1:50-1:250

-

Product Specifications

Species Reactivity

C. elegans

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide taken within amino acid region 50-100 on C. elegans CCR (yeast CCR4/NOT complex) protein.

Conjugate

Biotin Biotin Biotin

Form

Liquid

Concentration

0.5-1.5 mg/mL

Purification

Affinity chromatography

Storage buffer

proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Ccr4-Not complex is of interest to many groups because it regulates transcription, decay of mRNA, translation and even protein degradation. Ccr4-Not is a nine-subunit protein complex that is conserved in sequence and function throughout the eukaryotic kingdom. It has been reported to solely regulate transcription, it is now clear that it has much broader roles in gene regulation, such as in mRNA decay and quality control, RNA export, translational repression and protein ubiquitylation. The yeast Ccr4-Not complex contains nine conserved subunits: Not1, Not2, Not3, Not4/Mot2, Not5, Caf130, Caf40, Pop2/Caf1, and Ccr4.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.