Thermo Fisher Scientific MYOF Polyclonal Antibody
MYOF 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(P)에서 사용 가능. 인간, 생쥐, 랫트 반응성. PBS/glycerol buffer에 보관되며, -20°C에서 안정적. 근육막 관련 단백질 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MYOF (Accession Q9NZM1), corresponding to amino acid residues K1507–I1557. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850132 |
Product Specific Information
This antibody detects endogenous levels of total Myoferlin.
Target Information
Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles.
The protein encoded by this gene is a type II membrane protein structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes.
The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting involvement in membrane regeneration and repair.
Two transcript variants encoding different isoforms have been identified, and other possible variants have been detected but not fully characterized.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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