Thermo Fisher Scientific ELL Monoclonal Antibody (OTI2H7), TrueMAB
ELL 단백질을 표적으로 하는 Mouse IgG2b 단일클론 항체로, Western blot 및 IHC(Paraffin) 분석에 사용 가능. 인간 시료에 반응하며, 고순도 친화 크로마토그래피 정제. 안정적 액상 형태로 -20°C 보관.
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 302–621 of human ELL produced in E.coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Elongation factor component of the super elongation complex (SEC), which increases the catalytic rate of RNA polymerase II transcription by suppressing transient pausing. Also a component of the little elongation complex (LEC), regulating small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. Specifically required for stimulating the elongation step of snRNA gene transcription. ELL also stabilizes RNA polymerase II recruitment/initiation and entry into the pause site, contributing to pre-initiation complex stability and early elongation. [UniProt]
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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