Thermo Fisher Scientific Human SIRT2 Synthetic Peptide
Human SIRT2 단백질의 N-말단 17개 아미노산 서열로 구성된 합성 펩타이드로, PA5-20490 항체의 차단 펩타이드로 사용 가능. SIRT2 단백질 연구용으로 적합하며, 액상 형태로 제공되고 -20°C에서 보관.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the amino terminus of human SIRT2.
PEP-0610 can be used as a blocking peptide with polyclonal antibody PA5-20490.
Target Information
The SIRT2 protein (also known as Sirtuin for Silent Mating Type Information 2-Homolog) is a NAD-dependent deacetylase (NDAC) that controls gene silencing, cell cycle, and DNA damage repair. It may act as a tumor suppressor in human gliomas and serve as a molecular marker for these cells.
SIRT2 also functions as a redox sensor regulating muscle gene expression in response to food intake and exercise, and participates in the phosphorylation cascade during mitosis, being phosphorylated in late G2 phase, M phase, and cytokinesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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