Thermo Fisher Scientific Myelin Monoclonal Antibody (2B5)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

Immunohistochemistry (Paraffin) (IHC (P))

1:10

-

Immunohistochemistry (Frozen) (IHC (F))

1:10

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgM

Class

Monoclonal

Type

Antibody

Clone

2B5

Immunogen

Human myelin isolated from peripheral nervous system

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

ascites

Contains

0.09% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1077019

Product Specific Information

In paraffin sections antibody pm 43 recognizes only myelin in the peripheral nervous system (PNS). In frozen sections it also reacts with myelin in the central nervous system (CNS). Is useful for studying myelination and demyelination processes in the PNS, and remyelination processes in the CNS as can be observed after trauma in multiple sclerosis. Reacts with a 43 kD protein in immunoblotting.

Positive control: Peripheral nerve.

Target Information

Myelin is a membrane characteristic of the nervous tissue and functions as an insulator to increase the velocity of the stimuli being transmitted between a nerve cell body and its target. Myelin isolated from human and bovine nervous tissue is composed of approximately 80% lipid and 20% protein, and 30% of the protein fraction constitutes myelin basic protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.