Thermo Fisher Scientific JAKMIP2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human JAKMIP2. Recombinant protein control fragment (Product #RP-100239). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:JAKMIP2,uniProtId:Q96AA8-1,ncbiNodeId:9606,antigenRange:393-457,antigenLength:810,antigenImageFileName:PA5-61374_JAKMIP2_Q96AA8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-61374_JAKMIP2_Q96AA8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642843

Product Specific Information

Immunogen sequence: KLQVIEQQNI IDELTRDREK LIRRRKHRRS SKPIKRPVLD PFIGYDEDSM DSETSSMASF RTDRT

Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.

Target Information

JAKMIP2 (janus kinase and microtubule-interacting protein 2), also known as NECC1 (neuroendocrine long coiled-coil protein 1), CTCL tumor antigen HD-CL-04, JAMIP2 or KIAA0555, is a 810 amino acid protein belonging to the JAKMIP family. Localizing to the Golgi apparatus, JAKMIP2 is high expressed in brain, with moderate levels of expression found in thymus, spleen and lung. Existing as three alternatively spliced isoforms, the gene encoding JAKMIP2 maps to human chromosome 5q32 and mouse chromosome 18 B3. Chromosome 5 contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.