Thermo Fisher Scientific MPP2 Polyclonal Antibody

Applications

• Western Blot (WB): 1:500–1:3,000

Product Specifications

Product Specific Information

• Recommended positive controls: A549, HeLa, HCT116, mouse brain
• Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (82%), Bovine (98%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

The MAGUK (membrane-associated guanylate kinase homologs) family of proteins contain multiple protein-binding domains and are involved in cell junction organization, tumor suppression, and signaling.
The MAGUK family is divided into four subfamilies: DLG-like, ZO1-like, p55-like, and LIN2-like.
MPP2 (membrane protein, palmitoylated 2), also known as MAGUK p55 subfamily member 2, discs large homolog 2, or DLG2, is a 576 amino acid protein belonging to the MAGUK family that exists as three alternatively spliced isoforms.
MPP2 contains one guanylate kinase-like domain, a PDZ (DHR) domain, two L27 domains, and a single SH3 domain.
The gene encoding MPP2 maps to the same segment of human chromosome 17 as MPP3, with whom MPP2 likely shares similar function and common structural organization.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.