Thermo Fisher Scientific RAB8A Polyclonal Antibody
RAB8A 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot, IHC, ICC, Flow Cytometry에 적합합니다. Human 시료에 반응하며, 고순도의 Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Human RAB8A Recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2718459 |
Target Information
The protein encoded by this gene is a member of the RAS superfamily, which are small GTP/GDP-binding proteins with an average size of about 200 amino acids. The RAB/YPT family of RAS-related proteins may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi apparatus and the plasma membrane.
This protein shares 97%, 96%, and 51% similarity with dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively, and contains the four GTP/GDP-binding sites found in all RAS proteins. The putative effector-binding site is similar to that of RAB/YPT proteins.
Unlike most RAB proteins, this protein contains a C-terminal CAAX motif characteristic of many RAS superfamily members. Although isolated as a transforming gene from a melanoma cell line, no direct link between MEL and malignant melanoma has been demonstrated. This oncogene is located approximately 800 kb distal to MY09B on chromosome 19p13.1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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