Thermo Fisher Scientific Human YPEL4 Synthetic Peptide

Thermo Fisher Scientific Human YPEL4 Synthetic Peptide

Applications

• Control (Ctrl): Assay-dependent
• Blocking Assay (BLOCK): Assay-dependent

Product Specifications

Product Specific Information

This peptide corresponds to 12 amino acids near the amino terminus of human YPEL4.
PEP-1393 can be used as a blocking peptide with polyclonal antibody PA5-34350.

Target Information

YPEL4 (yippee-like 4) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division.
YPEL4 is ubiquitously expressed in adult tissues and has been shown to associate with the major vault protein (MVP). It has been suggested that MVP can inhibit YPEL4’s ability to activate Elk-1 in the MAPK signaling pathway.

Usage Note

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.