Thermo Fisher Scientific CATSPER3 Polyclonal Antibody
CATSPER3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 Immunocytochemistry에 적합하며, 인간 및 마우스 시료 반응성. 고순도 Affinity chromatography 정제, 1 mg/mL 농도, 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CATSPER3 (Accession Q86XQ3), corresponding to amino acid residues L183–Q233 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853049 |
Product Specific Information
Antibody detects endogenous levels of total CATSPER3.
Target Information
CatSpers (cation channel, sperm associated proteins) are ion transport proteins located on the surface of sperm cells in the principal piece of the sperm tail.
CatSpers are vital to sperm motility, fertilization, and cAMP-mediated calcium influx in sperm.
There are four CatSper proteins in mammalian sperm: CatSper1, CatSper2, CatSper3, and CatSper4.
CatSper proteins contain a single six-transmembrane-spanning segment and exhibit the voltage-dependent Ca²⁺ channel four-repeat structure.
They assemble into a heterotetrameric complex forming an alkalinization-activated Ca²⁺-selective channel.
Mutations in CatSper genes can result in male infertility.
CatSper3 plays an important role in hyperactivated motility of sperm cells, a process required for fertilization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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