Thermo Fisher Scientific EVC2 Polyclonal Antibody
Human EVC2 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:5,000~1:10,000 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. 골형성 및 골격 발달 관련 연구용 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human EVC2. Recombinant protein control fragment (Product # RP-99913) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2641146 |
Product Specific Information
Immunogen sequence:
QYESKLEPLP FTSADGVNED LSLNDQMIDI LSSEDPGSML QALEELEIAT LNRADADLEA CRTQISKDII ALLLKNLTSS GHLSPQV
Highest antigen sequence identity to the following orthologs:
- Mouse: 79%
- Rat: 78%
Target Information
This gene encodes a protein involved in bone formation and skeletal development. Mutations in this gene, as well as in a neighboring gene that lies in a head-to-head configuration, cause Ellis-van Creveld syndrome (chondroectodermal dysplasia), an autosomal recessive skeletal dysplasia.
Mutations in this gene also cause acrofacial dysostosis Weyers type (Curry-Hall syndrome), characterized by limb and facial abnormalities.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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