Thermo Fisher Scientific Human NTRK2 (TRKB), His Tag Recombinant Protein
인간 유래 NTRK2(TRKB) 단백질로, His-tag이 부착된 재조합 단백질입니다. 신경영양인자 BDNF 수용체 연구 및 키나아제 활성 분석에 적합합니다. 순수 정제된 액상 형태로 -80°C에서 보관하며 연구용으로만 사용됩니다.
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Thermo Fisher Scientific Human NTRK2 (TRKB), His Tag Recombinant Protein
Applications
- Kinase Assay (KA)
Tested Dilution
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | Insect cells |
| Amino Acid Sequence | 526–838 |
| Tag | His-tag |
| Molecular Weight | 40.9 kDa |
| Class | Recombinant |
| Type | Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See label |
| Purification | Purified |
| Storage Buffer | 50 mM Tris-HCl (pH 7.5), 0.05% Triton X-100, 300 mM NaCl, 0.5 mM EDTA, 2 mM DTT, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -80°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Dry ice |
Product Specific Information
- For maximum recovery, spin prior to use.
- Aliquots below 20 µL are not recommended.
- Do not store kinase diluted.
- If properly stored at -80°C, product is guaranteed for 6 months from purchase date.
- Protein Form: Cytoplasmic
Target Information
NTRK2 (TRKB) belongs to the neurotrophic factor family central to the development and maintenance of the mammalian nervous system. It acts as the receptor for brain-derived neurotrophic factor (BDNF). Together, NTRK2 and BDNF regulate short-term synaptic functions and long-term potentiation of brain synapses. TrkB is a tyrosine kinase gene expressed mainly in the central and peripheral nervous systems. Binding of neurotrophins induces phosphorylation of TrkB and downstream MAPK signaling, leading to cell differentiation. Mutations in TrkB are associated with obesity and mood disorders. Multiple splice variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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