Thermo Fisher Scientific Fibulin 1 Polyclonal Antibody
인간 Fibulin 1 단백질을 인식하는 Rabbit Polyclonal 항체. Western blot 및 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제. PBS, 40% glycerol, 0.02% sodium azide 포함. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Fibulin 1 (Product #RP-100522) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641631 |
Product Specific Information
Immunogen sequence:
NTLGSYLCSC SVGFRLSVDG RSCEDINECS SSPCSQECAN VYGSYQCYCR RGYQLSDVDG VTCEDIDECA LPTGGHICSY RCINIPGSFQ CSCPSSGYRL APNGRNCQDI DECVTGIHNC SINETCFNIQ GGFRCLAFEC PEN
Sequence identity:
- Mouse: 94%
- Rat: 94%
Target Information
Fibulin-1 is a modular glycoprotein component of the elastic extracellular matrix fibers, basement membranes, and blood. It self-associates and binds to calcium, fibronectin, laminin, nidogen, and fibrinogen. These interactions contribute to its association with basement membranes, connective tissue, elastic fibers, and fibrin clots. Fibulin-1 expression is stimulated by estrogen in ovarian cancer cell lines and may serve as an indicator of metastasis or cancer aggressiveness. Other studies suggest that Fibulin-1 inhibits cancer cell motility. The exact cellular function remains unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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