Thermo Fisher Scientific UBE2D1 Monoclonal Antibody (OTI1E7), TrueMAB
UBE2D1 단백질을 인식하는 마우스 단클론 항체로 Western blot에 최적화됨. 인간 단백질에 반응하며, 고순도의 액상 형태로 제공. PBS, BSA, 글리세롤 완충용액에 보관되며 -20°C에서 안정적. 연구용으로 단백질 유비퀴틴화 연구에 활용 가능.
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Applications
Tested Application
- Western Blot (WB): 1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E7 |
| Immunogen | Full length human recombinant protein of UBE2D1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The modification of proteins with ubiquitin is a key cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves three classes of enzymes:
- Ubiquitin-activating enzymes (E1s)
- Ubiquitin-conjugating enzymes (E2s)
- Ubiquitin-protein ligases (E3s)
This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The enzyme is closely related to a stimulator of iron transport (SFT) and is up-regulated in hereditary hemochromatosis. It also participates in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1α by interacting with E1 and E3 enzymes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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