Thermo Fisher Scientific PDE1A Monoclonal Antibody (OTI7D5), TrueMAB
PDE1A 단백질을 인식하는 Mouse monoclonal antibody로 Western blot과 IHC(Paraffin)에 적합합니다. Human 시료에 반응하며, 고순도 Affinity chromatography로 정제되었습니다. PBS/1% BSA/50% glycerol buffer에 보관되며 -20°C에서 안정적으로 유지됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7D5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 259–545 of human PDE1A produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5′-monophosphates. Members of the PDE1 family, such as PDE1A, are Ca²⁺/calmodulin-dependent enzymes that are activated by calmodulin in the presence of Ca²⁺ (Michibata et al., 2001).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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