Thermo Fisher Scientific PPP2R1B Polyclonal Antibody
PPP2R1B 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot, IHC, ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로 단백질 인산화 조절 연구에 적합합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:600 |
| Immunocytochemistry (ICC/IF) | 1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within human PPP2R1B aa 100–350 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol, 0.1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932486 |
Target Information
In eukaryotes, phosphorylation and dephosphorylation of proteins on serine and threonine residues regulate numerous cellular processes such as division, homeostasis, and apoptosis. Protein phosphatases play a key role in this regulation. The protein phosphatase (PP) holoenzyme is typically a trimeric complex consisting of a regulatory, variable, and catalytic subunit.
Major families of protein phosphatase catalytic subunits include PP1, PP2A, PP2B (calcineurin), and PP2C. An additional catalytic subunit, PPX (also known as PP4), is considered part of a novel PP family. The PP2A family includes subfamily members PP2A alpha and PP2A beta, which associate with various regulatory subunits such as PP2A-A alpha, PP2A-A beta, PP2A-B alpha, PP2A-B beta, PP2A-C alpha, PP2A-C beta, PP2A-B56 alpha, and PP2A-B56 beta.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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