Thermo Fisher Scientific SH3PXD2B Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

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Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SH3PXD2B. Recombinant protein control fragment (Product #RP-96944). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SH3PXD2B,uniProtId:A1X283-1,ncbiNodeId:9606,antigenRange:556-642,antigenLength:911,antigenImageFileName:PA5-57673_SH3PXD2B_A1X283-1_Rabbit.svg,antigenImageFileNamePDP:PA5-57673_SH3PXD2B_A1X283-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647252

Product Specific Information

Immunogen sequence: PPGVILPMMP AKHIPPARDS RRPEPKPDKS RLFQLKNDMG LECGHKVLAK EVKKPNLRPI SKSKTDLPEE KPDATPQNPF LKSRPQV

Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 80%.

Target Information

Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.