Thermo Fisher Scientific SH3PXD2B Polyclonal Antibody
SH3PXD2B 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody로, WB, IHC, ICC 등 다양한 응용에 적합. 인간 시료 반응성 확인됨. 항원 친화 크로마토그래피로 정제되었으며, 장기 보관 시 -20°C에서 안정적으로 유지.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | – |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | – |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SH3PXD2B. Recombinant protein control fragment (Product #RP-96944). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647252 |
Product Specific Information
Immunogen sequence:
PPGVILPMMP AKHIPPARDS RRPEPKPDKS RLFQLKNDMG LECGHKVLAK EVKKPNLRPI SKSKTDLPEE KPDATPQNPF LKSRPQV
Highest antigen sequence identity to the following orthologs:
- Mouse: 78%
- Rat: 80%
Target Information
Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation.
Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs), and phosphoinositides.
Acts as an organizer protein enabling NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and localization.
Plays a role in mitotic clonal expansion during the early stage of adipocyte differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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