Thermo Fisher Scientific EPHB4 Monoclonal Antibody (4G11)
인간 EPHB4 단백질을 인식하는 단클론 항체로, Western blot 및 ELISA에 적합합니다. Mouse IgG2b, kappa 아이소타입이며, 비결합형 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제되었으며, PBS(pH 7.4)에 보존제 없이 보관됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4G11 |
| Immunogen | EPHB4 (AAH52804, 198 a.a. ~ 323 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
AQLTVNLTRF PETVPRELVV PVAGSCVVDA VPAPGPSPSL YCREDGQWAE QPVTGCSCAP GFEAAEGNTK CRACAQGTFK PLSGEGSCQP CPANSHSNTI GSAVCQCRVG YFRARTDPRG APCTTP
Target Information
EPHB4 is a receptor tyrosine kinase belonging to the ephrin receptor family. Members of the Eph family play important roles in nervous system development, angiogenesis, and neural synapsis formation and maturation.
Ephrins are divided into two classes:
- Ephrin-A (EFNA): Anchored to the membrane by a glycosylphosphatidylinositol linkage
- Ephrin-B (EFNB): Transmembrane proteins
Eph receptors are grouped based on extracellular domain sequence similarity and ligand affinity. Ephrin receptors constitute the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB4 binds to ephrin-B2 and is essential for vascular development.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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