ELK Biotechnology NBK (phospho Ser35) rabbit pAb
NBK (phospho Ser35) rabbit pAb는 인산화된 NBK 단백질을 특이적으로 인식하는 항체로, IHC, IF, ELISA에 사용 가능. 인간, 쥐, 마우스 반응성. 폴리클로날 IgG 형태이며 -20°C에서 1년간 보관 가능. 세포 내막계 및 미토콘드리아 막에서 단백질 위치 탐지에 적합.
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제품명
NBK (phospho Ser35) rabbit pAb
기본 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | BIK; NBK; Bcl-2-interacting killer; Apoptosis inducer NBK; BIP1; BP4 |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | Immunohistochemistry: 1/100 - 1/300 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | Synthesized phospho-peptide around the phosphorylation site of human NBK (phospho Ser35) |
| Species | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 638 |
| Human Swiss-Prot No | Q13323 |
| Species Reactivity | Human; Rat; Mouse |
세포 내 위치
Endomembrane system; Single-pass membrane protein.
Mitochondrion membrane; Single-pass membrane protein.
Around the nuclear envelope, and in cytoplasmic membranes.
배경 정보
The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity and for interaction with anti-apoptotic members of the BCL2 family and viral survival-promoting proteins.
Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins.
[provided by RefSeq, Sep 2011]
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