
ELK Biotechnology NBK (phospho Thr33) rabbit pAb
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Product name: | NBK (phospho Thr33) rabbit pAb |
Alternative Names: | BIK; NBK; Bcl-2-interacting killer; Apoptosis inducer NBK; BIP1; BP4 |
Applications: | WB;IHC;IF;ELISA |
Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
Immunogen: | The antiserum was produced against synthesized peptide derived from human BIK around the phosphorylation site of Thr33. AA range:18-67 |
Storage: | Rabbit |
Storage: | -20°C/1 year |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1 mg/ml |
Observed Band: | 30kD |
GeneID(Human): | 638 |
Human Swiss-Prot No: | Q13323 |
Cellular localization: | Endomembrane system; Single-pass membrane protein. Mitochondrion membrane ; Single-pass membrane protein . Around the nuclear envelope, and in cytoplasmic membranes. |
Background: | The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins. [provided by RefSeq, Sep 2011], |
Species Reactivity: | Human;Rat;Mouse; |
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