ELK Biotechnology p70 S6 kinase α (phospho Ser371) rabbit pAb
p70 S6 kinase α (phospho Ser371)를 인식하는 토끼 폴리클로날 항체로, mTOR 신호전달 관련 단백질 인산화 연구에 적합. WB, IHC, IF, ELISA에 사용 가능. 고순도 IgG, -20°C에서 1년 보관 안정. Human, Mouse, Rat 반응성.
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p70 S6 kinase α (phospho Ser371) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | p70 S6 kinase α (phospho Ser371) rabbit pAb |
| Alternative Names | RPS6KB1; STK14A; Ribosomal protein S6 kinase beta-1; S6K-beta-1; S6K1; 70 kDa ribosomal protein S6 kinase 1; P70S6K1; p70-S6K 1; Ribosomal protein S6 kinase I; Serine/threonine-protein kinase 14A; p70 ribosomal S6 kinase alpha; p70 S6 kinase |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human p70 S6 Kinase around the phosphorylation site of Ser371. AA range: 337-386 |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 60 kD |
| Gene ID (Human) | 6198 |
| Human Swiss-Prot No. | P23443 |
| Cellular Localization | Cell junction, synapse, synaptosome, mitochondrion outer membrane, mitochondrion. Colocalizes with URI1 at mitochondrion. [Isoform Alpha I]: Nucleus, Cytoplasm. [Isoform Alpha II]: Cytoplasm. |
| Species Reactivity | Human; Mouse; Rat |
Background
Ribosomal protein S6 kinase B1 (RPS6KB1) Homo sapiens. This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]
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