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ELK Biotechnology p70 S6 kinase α (phospho Thr421) rabbit pAb
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인간 p70 S6 kinase α (phospho Thr421)를 인식하는 rabbit polyclonal antibody로 mTOR 신호 관련 단백질 연구에 적합. WB, IHC, IF, ELISA 등에 사용 가능. 고순도 IgG 형태로 -20°C에서 1년 보관 가능.
- 판매단위
- pk
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ELK Biotechnology ES7088-100UL p70 S6 kinase α (phospho Thr421) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES7088-50UL p70 S6 kinase α (phospho Thr421) rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology p70 S6 kinase α (phospho Thr421) rabbit pAb
ELK Biotechnology p70 S6 kinase α (phospho Thr421) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product Name | p70 S6 kinase α (phospho Thr421) rabbit pAb |
| Alternative Names | RPS6KB1; STK14A; Ribosomal protein S6 kinase beta-1; S6K-beta-1; S6K1; 70 kDa ribosomal protein S6 kinase 1; P70S6K1; p70-S6K 1; Ribosomal protein S6 kinase I; Serine/threonine-protein kinase 14A; p70 ribosomal S6 kinase alpha; p70 S6 kinas |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 Immunohistochemistry: 1/100–1/300 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized phospho-peptide around the phosphorylation site of human p70 S6 kinase α (phospho Thr421) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 70 kD |
| GeneID (Human) | 6198 |
| Human Swiss-Prot No. | P23443 |
| Cellular Localization | Cell junction, synapse, synaptosome, mitochondrion outer membrane, mitochondrion. Colocalizes with URI1 at mitochondrion. Isoform Alpha I: Nucleus, Cytoplasm. Isoform Alpha II: Cytoplasm. |
| Species Reactivity | Human; Mouse; Rat |
Background
Ribosomal protein S6 kinase B1 (RPS6KB1) is a member of the ribosomal S6 kinase family of serine/threonine kinases. It responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants and alternative translation start sites yield isoforms differing in N-termini and subcellular localization. Two pseudogenes for this gene are located on chromosome 17. (RefSeq, Jan 2013)
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