ELK Biotechnology Ribosomal Protein L22 rabbit pAb
Ribosomal Protein L22 rabbit pAb는 인간, 마우스, 랫트에 반응하는 다클론 항체입니다. IHC, IF, ELISA에 적합하며, 인간 RPL22 유래 합성 펩타이드로 제작되었습니다. 핵, 세포질, 리보솜 등 다양한 세포 위치에서 발현되는 단백질 검출에 활용됩니다.
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Ribosomal Protein L22 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Ribosomal Protein L22 rabbit pAb |
| Alternative Names | RPL22; 60S ribosomal protein L22; EBER-associated protein; EAP; Epstein-Barr virus small RNA-associated protein; Heparin-binding protein HBp15 |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | Immunohistochemistry: 1/100 - 1/300 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RPL22 (AA range: 51–100) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 6146 |
| Human Swiss-Prot No | P35268 |
| Cellular Localization | nucleus, cytoplasm, cytosol, ribosome, focal adhesion, cytosolic large ribosomal subunit, intracellular ribonucleoprotein complex, extracellular matrix, extracellular exosome |
| Species Reactivity | Human; Mouse; Rat |
Background
Ribosomes are organelles that catalyze protein synthesis, consisting of a small 40S subunit and a large 60S subunit. These subunits include 4 RNA species and around 80 distinct proteins. The RPL22 gene encodes a cytoplasmic ribosomal protein that is part of the 60S subunit and belongs to the L22E family. Its initiating methionine residue is post-translationally removed. The protein specifically binds Epstein-Barr virus-encoded RNAs (EBERs) 1 and 2, and the mouse protein can bind heparin. Transcript variants with alternative polyA signals exist, and multiple processed pseudogenes are dispersed throughout the genome. It was previously thought that this gene mapped to 3q26 and was fused to the acute myeloid leukemia 1 (AML1).
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