ELK Biotechnology RFC2 rabbit pAb
RFC2 단백질을 인식하는 토끼 다클론 항체로, WB 및 IHC 분석에 적합합니다. 인간, 생쥐, 랫트 시료에 반응하며 핵 내 단백질 검출에 사용됩니다. 고순도 IgG 형식으로 제공되며 -20°C에서 장기 보관 가능합니다.
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제품명
RFC2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | RFC2; Replication factor C subunit 2; Activator 1 40 kDa subunit; A1 40 kDa subunit; Activator 1 subunit 2; Replication factor C 40 kDa subunit; RF-C 40 kDa subunit; RFC40 |
| Applications | WB; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RFC2. AA range: 131–180 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 40 kDa |
| Gene ID (Human) | 5982 |
| Human Swiss-Prot No. | P35250 |
| Cellular Localization | Nucleus |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes a member of the activator 1 small subunits family. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). Replication factor C, also called activator 1, is a protein complex consisting of five distinct subunits. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP and may help promote cell survival. Disruption of this gene is associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene of this gene has been defined on chromosome 2. [provided by RefSeq, Jul 2013]
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