
ELK Biotechnology Rab 2A rabbit pAb
Rab 2A 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 적합합니다. 인간 RAB2A 유래 합성 펩타이드로 제작되었으며, ER-Golgi 간 단백질 운반 연구에 활용됩니다. Human, Mouse, Rat에 반응합니다.
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제품명
Rab 2A rabbit pAb
기본 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | RAB2A; RAB2; Ras-related protein Rab-2A |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RAB2A (AA range: 84–133) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 25 kD |
| GeneID (Human) | 5862 |
| Human Swiss-Prot No | P61019 |
| Species Reactivity | Human; Mouse; Rat |
세포 내 위치
Endoplasmic reticulum-Golgi intermediate compartment membrane; Lipid-anchor.
Melanosome; Endoplasmic reticulum membrane; Golgi apparatus membrane; Cytoplasmic vesicle, secretory vesicle, acrosome.
Localized in the Golgi apparatus in round spermatids and in the acrosome in elongating spermatids (By similarity).
Identified by mass spectrometry in melanosome fractions from stage I to IV (PubMed:17081065).
배경 (Background)
The protein encoded by this gene belongs to the Rab family, members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis.
Rabs are membrane-bound proteins involved in vesicular fusion and trafficking.
This protein resides in pre-Golgi intermediates and is required for protein transport from the endoplasmic reticulum (ER) to the Golgi complex.
Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
[provided by RefSeq, Oct 2011]
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