ELK Biotechnology CD45 (phospho Ser1007) rabbit pAb
CD45 (phospho Ser1007) rabbit polyclonal antibody는 인간 CD45 단백질의 Ser1007 인산화 부위를 인식합니다. WB, IF, ELISA에 적합하며, 세포막 단백질 분석에 활용됩니다. T/B 세포 항원 수용체 및 사이토카인 신호 조절 연구에 유용합니다.
- 카탈로그번호
- ES6941-xxxxx (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology CD45 (phospho Ser1007) rabbit pAb
CD45 (phospho Ser1007) rabbit pAb
제품 개요
CD45 (phospho Ser1007) rabbit polyclonal antibody는 인간 CD45 단백질의 Ser1007 인산화 부위를 표적하는 항체로, 세포 신호전달 및 면역세포 활성 조절 연구에 적합합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | CD45 (phospho Ser1007) rabbit pAb |
| Alternative Names | PTPRC; CD45; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; L-CA; T200; CD antigen CD45 |
| Applications | WB; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human CD45 around phosphorylation site of Ser1007 (AA range: 981–1030) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 150 kD |
| GeneID (Human) | 5788 |
| Human Swiss-Prot No | P08575 |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein; Membrane raft; Colocalized with DPP4 in membrane rafts |
| Species Reactivity | Human; Mouse; Rat |
Background
The CD45 protein belongs to the protein tyrosine phosphatase (PTP) family, which regulates various cellular processes such as cell growth, differentiation, mitosis, and oncogenic transformation. It contains an extracellular domain, a single transmembrane segment, and two tandem intracytoplasmic catalytic domains, classifying it as a receptor-type PTP. CD45 is a key regulator of T- and B-cell antigen receptor signaling and modulates Src family kinases as well as JAK kinases, thereby controlling cytokine receptor signaling. Alternative splicing of this gene results in multiple transcript variants.
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.