ELK Biotechnology FAK (phospho Ser910) rabbit pAb
FAK (phospho Ser910) rabbit pAb는 인간 FAK 단백질의 Ser910 인산화 부위를 인식하는 고품질 폴리클로날 항체입니다. IHC, IF, ELISA에 적합하며 세포 접착 및 신호전달 연구에 활용됩니다. -20°C에서 1년간 안정적으로 보관 가능합니다.
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FAK (phospho Ser910) rabbit pAb
제품 개요
이 항체는 인간 FAK 단백질의 Ser910 인산화 부위 주변에서 합성된 펩타이드로부터 생성된 rabbit polyclonal antibody입니다. 세포 접착 및 신호전달 경로 연구에 유용하며, 다양한 종에서 반응성을 보입니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | FAK (phospho Ser910) rabbit pAb |
| Alternative Names | PTK2; FAK; FAK1; Focal adhesion kinase 1; FADK 1; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | Immunohistochemistry: 1/100–1/300 Immunofluorescence: 1/200–1/1000 ELISA: 1/5000 Other applications not yet tested |
| Immunogen | Synthesized peptide derived from human FAK around phosphorylation site of Ser910 (AA range: 876–925) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 5747 |
| Human Swiss-Prot No | Q05397 |
| Cellular Localization | Cell junction, focal adhesion, cell membrane (cytoplasmic side), cytoplasm, cytoskeleton, microtubule organizing center (centrosome), nucleus, cilium basal body; constituent of focal adhesions; detected at microtubules |
| Species Reactivity | Human; Mouse; Rat |
Background
Protein tyrosine kinase 2 (PTK2) is a cytoplasmic protein tyrosine kinase concentrated in focal adhesions formed between cells and extracellular matrix constituents. It belongs to the FAK subfamily and plays a crucial role in cell growth and signal transduction pathways activated by neural peptides or extracellular matrix interactions. Multiple transcript variants encoding different isoforms have been identified, with four full-length forms determined (RefSeq, Oct 2015).
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