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ELK Biotechnology FAK (phospho Tyr577) rabbit pAb
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FAK (phospho Tyr577) rabbit polyclonal antibody로, 인간·마우스·랫트 시료에 반응합니다. WB, IHC, IF, ELISA에 사용 가능하며, 세포 접착 및 신호전달 연구에 적합합니다. 합성 인산화 펩타이드 항원으로 제작되어 높은 특이성을 제공합니다.
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ELK Biotechnology ES6904-100UL FAK (phospho Tyr577) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES6904-50UL FAK (phospho Tyr577) rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology FAK (phospho Tyr577) rabbit pAb
FAK (phospho Tyr577) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | FAK (phospho Tyr577) rabbit pAb |
| Alternative Names | PTK2; FAK; FAK1; Focal adhesion kinase 1; FADK 1; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | IHC: 1/100–1/300, ELISA: 1/20000. Other applications not yet tested. |
| Immunogen | Synthesized peptide derived from human FAK around the phosphorylation site of Tyr577 (AA range: 543–592). |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Gene ID (Human) | 5747 |
| Human Swiss-Prot No. | Q05397 |
| Species Reactivity | Human; Mouse; Rat |
| Cellular Localization | Cell junction, focal adhesion, cell membrane (cytoplasmic side), cytoplasm (cell cortex, cytoskeleton, centrosome, cilium basal body), nucleus. Constituent of focal adhesions and detected at microtubules. |
Background
Protein tyrosine kinase 2 (PTK2), also known as focal adhesion kinase (FAK), is a cytoplasmic protein tyrosine kinase concentrated in focal adhesions formed between cells and extracellular matrix components. It belongs to the FAK subfamily of protein tyrosine kinases and plays a key role in cell growth and intracellular signal transduction pathways initiated by neural peptides or cell–matrix interactions. Multiple transcript variants encoding different isoforms have been identified for this gene (RefSeq, Oct 2015).
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