ELK Biotechnology FAK (phospho Tyr925) rabbit pAb
FAK 단백질의 Tyr925 인산화 부위를 인식하는 rabbit polyclonal antibody. WB, IHC, IF, ELISA에 적합하며, 세포 접착 및 신호전달 연구에 활용 가능. Human, Mouse, Rat 시료에 반응.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology FAK (phospho Tyr925) rabbit pAb
FAK (phospho Tyr925) rabbit pAb
제품 개요
FAK (Focal Adhesion Kinase)은 세포 접착과 신호전달에 중요한 역할을 하는 단백질로, 본 항체는 Tyr925 인산화 부위를 특이적으로 인식하는 rabbit polyclonal antibody입니다. 다양한 응용 분야(WB, IHC, IF, ELISA)에 사용 가능합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | FAK (phospho Tyr925) rabbit pAb |
| Alternative Names | PTK2; FAK; FAK1; Focal adhesion kinase 1; FADK 1; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human FAK around the phosphorylation site of Tyr925 (AA range: 892–941) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 125 kDa |
| Gene ID (Human) | 5747 |
| Human Swiss-Prot No. | Q05397 |
| Cellular Localization | Cell junction, focal adhesion, cell membrane (cytoplasmic side), cytoplasm (cell cortex, cytoskeleton, centrosome, cilium basal body), nucleus. Constituent of focal adhesions; detected at microtubules. |
| Species Reactivity | Human; Mouse; Rat |
Background
Protein tyrosine kinase 2 (PTK2) is a cytoplasmic protein tyrosine kinase concentrated in focal adhesions formed between cells and extracellular matrix components. It belongs to the FAK subfamily of tyrosine kinases and plays a key role in cell growth and intracellular signaling pathways. Activation of PTK2 is an early step in signaling triggered by neural peptides or cell-matrix interactions. Multiple transcript variants encoding different isoforms have been identified.
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.