ELK Biotechnology PAK5/6 (phospho Ser602/S560) rabbit pAb
PAK5/6 인산화(Ser602/S560) 특이 토끼 다클론 항체로, WB 및 ELISA에 적합합니다. 세포 생존, 신경 돌기 성장 및 세포골격 조절 관련 연구에 활용 가능하며, 인간 및 생쥐 시료에 반응합니다.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology PAK5/6 (phospho Ser602/S560) rabbit pAb
제품명
PAK5/6 (phospho Ser602/S560) rabbit pAb
공급업체
ELK Biotechnology
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | PAK7; KIAA1264; PAK5; Serine/threonine-protein kinase PAK 7; p21-activated kinase 5; PAK-5; p21-activated kinase 7; PAK-7; PAK6; Serine/threonine-protein kinase PAK 6; p21-activated kinase 6; PAK-6 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human PAK5/6 around phosphorylation site of Ser602/Ser560 (AA range: 566–615) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 75 kD |
| GeneID (Human) | 57144 / 56924 |
| Human Swiss-Prot No | Q9P286 / Q9NQU5 |
| Species Reactivity | Human; Mouse |
| Cellular Localization | Mitochondrion, Cytoplasm, Nucleus. Shuttles between nucleus and mitochondria; mitochondrial localization is essential for its role in cell survival. |
Background
This protein belongs to the PAK family of Ser/Thr protein kinases, which act as effectors of Rac/Cdc42 GTPases involved in cytoskeletal dynamics, proliferation, and cell survival signaling.
It contains a CDC42/Rac1 interactive binding (CRIB) motif and binds CDC42 in the presence of GTP.
Predominantly expressed in brain, it promotes neurite outgrowth and may play a role in neurite development.
Associated with microtubule networks, it induces microtubule stabilization.
Subcellular localization is tightly regulated during cell cycle progression.
Alternatively spliced transcript variants encoding the same protein have been described. (RefSeq, Jul 2008)
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.