
ELK Biotechnology MEK-6 (phospho Ser207) rabbit pAb
MEK-6 (phospho Ser207) rabbit polyclonal antibody로, 인산화된 Ser207 부위를 특이적으로 인식합니다. WB, IHC, IF, ELISA에 사용 가능하며, 인간, 마우스, 랫트 시료에 반응합니다. 세포 스트레스 및 신호전달 연구에 적합합니다.
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MEK-6 (phospho Ser207) rabbit pAb
제품 개요
MEK-6 (phospho Ser207) rabbit polyclonal antibody는 인간 MEK-6 단백질의 Ser207 인산화 부위를 인식하도록 제작되었습니다. MAPK 신호전달 경로 연구 및 세포 스트레스 반응 분석에 유용합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | MEK-6 (phospho Ser207) rabbit pAb |
| Alternative Names | MAP2K6; MEK6; MKK6; PRKMK6; SKK3; Dual specificity mitogen-activated protein kinase kinase 6; MAP kinase kinase 6; MAPKK 6; MAPK/ERK kinase 6; MEK 6; Stress-activated protein kinase kinase 3; SAPK kinase 3; SAPKK-3; SAPKK3 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000; IHC: 1/100–1/300; ELISA: 1/40000; Other applications not yet tested |
| Immunogen | Synthesized phospho-peptide around the phosphorylation site of human MEK-6 (phospho Ser207) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Gene ID (Human) | 5608 |
| Human Swiss-Prot No. | P52564 |
| Cellular Localization | Nucleus; Cytoplasm; Cytoskeleton; Binds to microtubules |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of the p38 MAP kinase-mediated signal transduction pathway, this gene is involved in many cellular processes such as stress-induced cell cycle arrest, transcription activation, and apoptosis.
[Provided by RefSeq, Jul 2008]
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