ELK Biotechnology MEK-1 (phospho Thr386) rabbit pAb
MEK-1 (phospho Thr386) rabbit pAb는 MAP2K1 인산화 부위를 인식하는 폴리클로날 항체로, WB와 ELISA에 적합합니다. 세포 내 MAPK 신호전달 경로 연구에 활용되며, 인간, 마우스, 랫트 시료에 반응합니다. -20°C에서 1년 보관 가능합니다.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology MEK-1 (phospho Thr386) rabbit pAb
제품명
MEK-1 (phospho Thr386) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MAP2K1 around the phosphorylation site of Thr386. AA range: 344-393 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 45 kD |
| Gene ID (Human) | 5604 |
| Human Swiss-Prot No. | Q02750 |
| Cellular Localization | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome; spindle pole body; nucleus; membrane (peripheral membrane protein). Localizes at centrosomes during prometaphase, midzone during anaphase, and midbody during telophase/cytokinesis (PubMed:14737111). Membrane localization is probably regulated by its interaction with KSR1 (PubMed:10409742). |
| Species Reactivity | Human; Mouse; Rat |
Background
The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon a wide variety of extra- and intracellular signals. As an essential component of the MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation, and development.
[provided by RefSeq, Jul 2008]
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.