ELK Biotechnology MRP-S18A rabbit pAb
MRP-S18A rabbit polyclonal antibody로 인간, 마우스, 랫트 시료에 반응합니다. IHC, IF, ELISA에 사용 가능하며, 미토콘드리아 단백질 MRPS18A 인식. 고순도 IgG, 1 mg/ml 농도, -20°C에서 1년 안정 저장.
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제품명
MRP-S18A rabbit pAb
주요 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | MRPS18A; 28S ribosomal protein S18a; mitochondrial; MRP-S18-a; Mrps18a; S18mt-a; 28S ribosomal protein S18-3, mitochondrial; MRP-S18-3 |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | Immunohistochemistry: 1/100 - 1/300 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MRPS18A (AA range: 81–130) |
| Species Reactivity | Human; Mouse; Rat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 27–30 kD |
| GeneID (Human) | 55168 |
| Human Swiss-Prot No | Q9NVS2 |
| Cellular Localization | Mitochondrion |
| Storage | -20°C / 1 year |
| Host | Rabbit |
배경 설명
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence and biochemical properties, preventing easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family and is one of three with significant sequence similarity to bacterial S18 proteins.
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